21 resultados para Virus del papiloma humano

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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Background: The possibility to acquire sexually transmitted diseases generates bio-psycho-social conflicts affecting daily life of women. Objective: To investigate the knowledge of women on the concept of being infected by the human papilloma virus (HPV) and to understand the significance they attributed to their condition as HPV carriers. Material and method: It is a qualitative study in which ten women were interviewed, after the result of a cytopathological exam suggesting HPV. Data were collected at the Center of Health School of the Universidade Estadual Paulista -UNESP-Brazil. Results: The significant items were: deception and preoccupation about the cure, since they indicate that it is very deceptive to be infected with an incurable disease by a person whom they trust; the method of having sexual relations and being infected again; the necessity of care and of being optimistic to face the disease and the threat of cervix cancer originating anxiety. Discussion: Orientations made by health professionals were efficacious to clarify the relationship with cancer development. It is possible to understand the necessity of assistance orientations and the opportunity to hear them, offering individualized quality care. This study also offers important elements to reinforce the educational role of health professionals, principally those referring to sexually transmitted infection and cancer, seeking prevention and early treatment with the offered information. However, there is no desire of finishing the subject regarding perception, thus there is much to discover about diseases related to human papilloma virus. Key words: women carriers of HPV, feelings attributed by women.

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Report of an experience of nursing students in providing care to a patient with epidermodysplasia verruciformis, during the internship in the discipline Nursing in Transmittable Diseases, at the dermatology ward of a teaching hospital, located in the state of São Paulo, Brazil, in 2009. This is a rare genodermatosis, susceptible to infection with different types of human papilloma viruses, that cause exacerbated physical changes that impact the psyche of the affected individual. Care delivery was based on the assistance complexity indicated by the application of the Patient Classification System proposed by Perroca. The experience allowed students to learn how to cope with a patient affected by a rare and complex disease, of difficult resolution, and to provide integral care to this individual, perceiving him beyond the lesions. One conclude that the experience has greatly contributed to the growth of the students as future professionals.

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The recognition of emissary foramens is important not only for understanding the regional neurovascular anatomy, but also to distinguish normal from potentially abnormal structures. Thus, the aim of this study was to review the literature on anatomical and clinical aspects of the mastoid, parietal and sphenoid emissary foramens. It was found that the emissary foramen presents importance in clinical practice because it acts as a route of spread of extracranial infection to the intracranial structures and also possible complications in neurosurgery, due to its influence in the performance of techniques such as radiofrequency rhizotomy for treatment of trigeminal neuralgia. The anatomical knowledge of the emissary foramens is important due to variability in their incidence in the human skull and its relation to the dura mater sinuses.

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Câncer cervical é o segundo tipo mais comum em mulheres no mundo. Estudos apontam que a presença de certos tipos do HPV desempenha um papel central na formação do câncer. Apesar do grande sucesso da prevenção do câncer uterino com vacinas, o uso de produtos naturais para o tratamento de doenças é crescente e de grande importância econômica. Alcalóides guanidínicos isolados de Pterogyne nitens representam uma potencial fonte de novos tratamentos. O objetivo geral desse trabalho foi avaliar a atividade apoptótica induzida em células de carcinoma cervical infectadas (SiHa) e não infectadas pelo HPV (C33-A), tratadas com nitensidinas A e B, isoladas de folhas de Pterogyne nitens Tul. A citotoxicidade dos alcalóides foi avaliada utilizando o método de MTT. Para avaliar quantitativamente a apoptose e necrose celular, foi executado o ensaio de Anexina V por citometria de fluxo. Ambas as substâncias, nitensidinas A e B, apresentaram efeito citotóxico concentração-resposta em ambas as linhagens testadas (SiHa e C33A) e nos dois tempos de tratamento (24 horas e 48 horas). Não foi observada significância estatística quando comparados os perfis de ação citotóxica das duas substâncias em teste (nitensidinas A e B), em nenhuma das linhagens testadas (SiHa e C33A) e em nenhum dos dois tempos de tratamento (24 horas e 48 horas). Ambas as substâncias, nitensidina A e nitensidina B, apresentaram efeito indutor de apoptose precoce e, em menor número, de apoptose tardia/ necrose, em ambas as linhagens testadas (SiHa e C33A) e nos dois tempos de tratamento (24 horas e 48 horas)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Biociências e Biotecnologia Aplicadas à Farmácia - FCFAR

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Patologia - FMB

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)